Hydrochloric Acid → HCID 15076055, compound

Participants

Reaction Conditions

Reaction Steps

L-phenylalanine (50 gm) in water (50 mL) was stirred for about 30 minutes and reaction mass was cooled to 10-15° C. To the resulting solution, aq. NaOH was added followed by addition of isobutylchloroformate (45.5 gm). The reaction mass was stirred at about 25° C. for about 3-4 h and pH was adjusted to 2-3 by addition of conc. HCl at 10-15° C. Reaction mass was stirred at 10-15° C. for 1 h, filtered, washed with water and dried to obtain the title compound.

Provenance & Evidence