Boron trifluoride → 2-Propenoic acid, 2-methyl-, tetrahydro-5-oxo-3-furanyl ester
Reaction equation
[C:1]([O:6][CH2:7][CH:8]1[O:12][C:10](=[O:11])[CH2:9]1)(=[O:5])[C:2]([CH3:4])=[CH2:3].B(F)(F)F>C1(C)C=CC=CC=1>[C:1]([O:6][CH:7]1[CH2:8][O:12][C:10](=[O:11])[CH2:9]1)(=[O:5])[C:2]([CH3:4])=[CH2:3]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 30 °C
Procedure
In a 20 mL Schlenk flask, 2.0 g of crude β-methacryloyloxymethyl-β-propiolactone was put, and dissolved in 8.0 g of toluene. Further, 54 μL of diethyl ether complex of boron trifluoride was added thereto, and the resulting mixture was warmed to 30° C. and stirred. After the mixture was stirred for 2 hours, the resulting reaction mixture was washed with a 10% sodium hydrogen carbonate aqueous solution and saturated brine, and dried over magnesium sulfate. After separation by filtration, the solvent was distilled off using an evaporator to give 1.1 g of crude β-methacryloyloxy-γ-butyrolactone represented by formula (10). FIG. 3 shows an NMR measurement chart.
Workup
- stirringAfter the mixture was stirred for 2 hours
- customthe resulting reaction mixture
- washwas washed with a 10% sodium hydrogen carbonate aqueous solution and saturated brine
- dry with materialdried over magnesium sulfate
- customAfter separation
- filtrationby filtration
- distillationthe solvent was distilled off
- customan evaporator
Sources & evidence
- ORD record
- ord-64390162edaf468e91ddd3c8a63dff37
- Source dataset
- uspto-grants-2016_05
- Patent number
- US09346775B2
Reaction notes
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