HCID 71295204, compound → HCID 89429163, compound

HRID 527184Notes

Reaction equation

HRID 527184 reaction equation
[CH:1]1([N:7]2[C:11](=[O:12])[N:10]([C:13]3[CH:18]=[CH:17][C:16]([N:19]4[CH2:24][CH2:23][N:22]([C:25]5[CH:30]=[CH:29][C:28]([O:31]C)=[CH:27][CH:26]=5)[CH2:21][CH2:20]4)=[CH:15][CH:14]=3)[CH:9]=[N:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>Br>[CH:1]1([N:7]2[C:11](=[O:12])[N:10]([C:13]3[CH:18]=[CH:17][C:16]([N:19]4[CH2:20][CH2:21][N:22]([C:25]5[CH:26]=[CH:27][C:28]([OH:31])=[CH:29][CH:30]=5)[CH2:23][CH2:24]4)=[CH:15][CH:14]=3)[CH:9]=[N:8]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 1

HCID 71295204HCID 71295204, compound

Product 1

HCID 89429163HCID 89429163, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

This compound was synthesized as a white amorphous solid from 4k (24.2 mg, 0.056 mmol) in 48% aqueous HBr (1.0 mL) in 92% yield by following general procedure 1.4: MALDI-MS: 420.2 (M+H+), 442.2 (M+Na+).

Sources & evidence

ORD record
ord-da7dd4f5aa2d4dd987a0dd11040bd2ed
Source dataset
uspto-grants-2016_05
Patent number
US09346791B2

Reaction notes

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