HCID 90310574, compound → HCID 90310581, compound

HRID 527186Notes

Reaction equation

HRID 527186 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([C:15]3[CH:20]=[CH:19][C:18]([N:21]4[C:25](=[O:26])[N:24]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[N:23]=[CH:22]4)=[CH:17][CH:16]=3)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1>Br>[OH:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:10][CH2:11][N:12]([C:15]3[CH:16]=[CH:17][C:18]([N:21]4[C:25](=[O:26])[N:24]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])[N:23]=[CH:22]4)=[CH:19][CH:20]=3)[CH2:13][CH2:14]2)=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 90310574HCID 90310574, compound

Product 1

HCID 90310581HCID 90310581, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

This compound was synthesized as a white amorphous solid from 4m (50.2 mg, 0.108 mmol) in 48% aqueous HBr (1.0 mL) in 95% yield by following general procedure 1.4: MALDI-MS: 450.3 (M+H+), 472.3 (M+Na+).

Sources & evidence

ORD record
ord-4dc72a91614946e29c0b5a043ada7b07
Source dataset
uspto-grants-2016_05
Patent number
US09346791B2

Reaction notes

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