反应详情

To a stirred suspension of compound 3 (0.2 g, 0.6 mmol) and palladium catalyst (10% Pd on carbon 0.04 g) in ethanol (6 mL), hydrazine monohydrate (0.29 mL, 5.7 mmol) was added slowly and the reaction mixture was heated to reflux for 4 h. After cooling to room temperature, the reaction mixture was filtered and the filtrate was concentrated to obtain amine 4 (0.17 g, 93%).

1. additionwas added slowly
2. temperaturethe reaction mixture was heated
3. temperatureto reflux for 4 h
4. filtrationthe reaction mixture was filtered
5. concentrationthe filtrate was concentrated