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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527355Generated: October 30, 2026

2-(4-(N-cyano-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dione → 2-(5-(N-Cyano-S-methylsulfonimidoyl)pyridin-2-yl)-isoindole-1,3-dione

https://huagongshe.com/reaction/527355

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-(N-cyano-S-methylsulfonimidoyl)benzyl)isoindoline-1,3-dioneHCID 86711610—
ReactantHCID 86711626HCID 86711626—
Product2-(5-(N-Cyano-S-methylsulfonimidoyl)pyridin-2-yl)-isoindole-1,3-dioneHCID 86711625—

Reaction Steps

The title compound is prepared in analogy to preparation 6c, substituting 2-(4-(N-cyano-S-methylsulfinimidoyl)benzyl)isoindoline-1,3-dione with 2-(5-(N-cyano-S-methylsulfinimidoyl)pyridin-2-yl)-isoindole-1,3-dione (preparation 16c). ESI mass spectrum: [M+H]+=341; r.t. HPLC: 0.88 min (Z018_S04).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346794B1
Source datasetuspto-grants-2016_05
ORD IDord-dc048a09b9174a9199efc02fb2bec3b0
Source noteuspto-grants-2016_05