Piperidine → HCID 59252617, compound

HRID 527845Notes

Reaction equation

HRID 527845 reaction equation
Cl[CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:14]([O:15]C)=[N:13][C:12]2[C:7]1=[N:8][C:9]([NH:18][C@H:19]([CH3:23])[CH2:20][CH2:21][CH3:22])=[N:10][C:11]=2[NH2:17].[NH:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[NH2:17][C:11]1[N:10]=[C:9]([NH:18][C@H:19]([CH3:23])[CH2:20][CH2:21][CH3:22])[N:8]=[C:7]2[C:12]=1[NH:13][C:14](=[O:15])[N:6]2[CH2:5][CH2:4][CH2:3][CH2:2][N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 59252640HCID 59252640, compound

Product 1

HCID 59252617HCID 59252617, compound

Procedure

Prepared similarly to Example 29 from 9-(4-chlorobutyl)-N2-[(1R)-1-methylbutyl]-8-(methyloxy)-9H-purine-2,6-diamine and piperidine.

Sources & evidence

ORD record
ord-7432351978284b998f61fb695434cc4b
Source dataset
uspto-grants-2016_05
Patent number
US09346806B2

Reaction notes

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