Diethyl Malonate → Isobutylglutaric acid

HRID 52790Notes

Reaction equation

HRID 52790 reaction equation
C([O:3][C:4](=[O:13])[C:5](C#N)=[CH:6][CH2:7][CH:8]([CH3:10])[CH3:9])C.C(OCC)(=O)[CH2:15][C:16]([O:18]CC)=[O:17]>>[CH2:7]([CH:6]([CH2:5][C:4]([OH:3])=[O:13])[CH2:15][C:16]([OH:18])=[O:17])[CH:8]([CH3:9])[CH3:10]

Participants

3

Reactant 2

HCID 7761Diethyl MalonateHCID 543880392-Cyano-5-methylhex-2-enoic acid ethyl ester

Product 1

HCID 10976240Isobutylglutaric acid

Procedure

Reacting the 2-cyano-5-methylhex-2-enoic acid ethyl ester with diethyl malonate to form 3-isobutylglutaric acid;

Sources & evidence

ORD record
ord-276ed5a635ba4cde8555de4c00e585ae
Source dataset
uspto-grants-1997_04
Patent number
US05616793

Reaction notes

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