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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527903Generated: October 31, 2026

HCID 68027538, compound → HCID 68027541, compound

https://huagongshe.com/reaction/527903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68027538HCID 68027538—
CatalystNickelHCID 935—
SolventMethanolHCID 887—
ProductHCID 68027541HCID 68027541—

Reaction Steps

To a solution of (R)-methyl-(5-nitro-pyridin-2-yl)-{1-[7-(2-trimethylsilanyl-ethoxymethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-pyrrolidin-3-yl}-amine (10 mmol) in methanol (100 mL) was added Raney Ni. The mixture was stirred at room temperature for 18 hours under 1 atm of H2. After filtration, it was concentrated to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346810B2
Source datasetuspto-grants-2016_05
ORD IDord-21604ce5c289404896fd5be45bb60424
Source noteuspto-grants-2016_05