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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527905Generated: October 26, 2026

6-Bromopyridine-3-carbonitrile → (R)-tert-butyl 3-((5-cyanopyridin-2-yl)(cyclopropyl)amino)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/527905

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromopyridine-3-carbonitrileHCID 5005718—
Reactant(R)-tert-Butyl 3-(cyclopropylamino)pyrrolidine-1-carboxylateHCID 53346626—
Product(R)-tert-butyl 3-((5-cyanopyridin-2-yl)(cyclopropyl)amino)pyrrolidine-1-carboxylateHCID 66766463—

Reaction Steps

The title compound was prepared according to the procedures of Intermediate 2 (A) using (R)-tert-butyl 3-(cyclopropylamino)pyrrolidine-1-carboxylate and 6-bromonicotinonitrile under similar conditions MS (m/z): 329 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346810B2
Source datasetuspto-grants-2016_05
ORD IDord-2ac062a8d31b4cc883a59433c782e1fa
Source noteuspto-grants-2016_05