Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 527938Generated: November 1, 2026

1,1'-Carbonyldiimidazole → HCID 86692157, compound

https://huagongshe.com/reaction/527938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
ReactantHCID 68027261HCID 68027261—
SolventTetrahydrofuranHCID 8028—
ProductHCID 86692157HCID 86692157—

Reaction Steps

A solution of (R)—N2-(1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-3-yl)-N2-methylpyridine-2,5,6-triamine (35 mg, 0.11 mmol,) and 1,1′-carbonyldiimidazole (21 mg, 0.13 mmol) in tetrahydrofuran (3.0 mL) was stirred at reflux for 1 h. The volatiles were removed and the residue was purified by chromatography to give the title compound. MS (m/z): 351 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346810B2
Source datasetuspto-grants-2016_05
ORD IDord-6bd4e2d7e2264859b3ee432471fc190c
Source noteuspto-grants-2016_05