反应详情

To a suspension of Example 83A (370 mg, 0.970 mmol) in 15 mL dichloromethane was added excess trifluoroacetic acid. The reaction was held at room temperature overnight. The volatiles were removed in vacuo, and the residue was dissolved in 30 mL ethyl acetate. The mixture was washed with saturated sodium bicarbonate and brine, dried over magnesium sulfate, and concentrated to give the title compound. MS (ESI+) m/z 338.2 (M+H)+.

1. customThe volatiles were removed in vacuo
2. dissolutionthe residue was dissolved in 30 mL ethyl acetate
3. washThe mixture was washed with saturated sodium bicarbonate and brine
4. dry with materialdried over magnesium sulfate
5. concentrationconcentrated