HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 89705133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl (2S)-2-carbamoyl-4,4-difluoropyrrolidine-1-carboxylate | HCID 45158906 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 89705133 | HCID 89705133 | — |
Reaction Steps
9.54 mL of trifluoroacetic acid was added to a solution of (S)-tert-butyl 2-carbamoyl-4,4-difluoropyrrolidine-1-carboxylate (1.25 g, 5 mmol) in 10 mL of dichloromethane. The solution was stirred for 1 hour before evaporation. The residue was washed with ether to yield white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346814B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-80f563729f9a4aeaad76a785a8b82381 |
| Source note | uspto-grants-2016_05 |