1-tert-Butyl 4-ethyl 5-oxoazepane-1,4-dicarboxylate → HCID 178451648, compound

Participants

Reaction Conditions

Reaction Steps

To 13.3 g (46.61 mmol) 5-oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester in 8 mL acetic acid was added 3.87 g (46.61 mmol) 3-aminopyrazole and the reaction mixture was heated at 80° C. for 15 minutes. The resulting solid was collected by filtration and washed with TBME (3×10 mL) to give the desired product.

Provenance & Evidence