Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 528718Generated: October 31, 2026

Azetidine → 10-Azetidin-1-yl-3-iodo-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/528718

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzetidineHCID 10422—
Reactant10-Chloro-3-iodo-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl esterHCID 86667170—
Product10-Azetidin-1-yl-3-iodo-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl esterHCID 67979462—

Reaction Steps

The product was prepared using 10-chloro-3-iodo-5,6,8,9-tetrahydro-1,4,7,10a-tetraaza-cyclohepta[f]indene-7-carboxylic acid tert-butyl ester and azetidine as the amine in route 1 (step e).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346816B2
Source datasetuspto-grants-2016_05
ORD IDord-03d98210bcdd48a38143533652eba734
Source noteuspto-grants-2016_05