HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 3-Benzothiazol-2-yl-azetidine trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 3-Benzothiazol-2-yl-azetidine-1-carboxylic acid tert-butyl ester | HCID 44239818 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Benzothiazol-2-yl-azetidine trifluoroacetate | HCID 67458761 | — |
Reaction Steps
To 48 mg (166 μmol) 3-benzothiazol-2-yl-azetidine-1-carboxylic acid tert-butyl ester was added 5 mL DCM and 5 mL TFA. The resulting mixture was stirred at room temperature for 30 minutes. The solvent was evaporated to give the product as the TFA salt which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346816B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-f3496f97b59944cf94bf5c815d221f4b |
| Source note | uspto-grants-2016_05 |