HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4,4,4-Trifluoro-N-(4,4,4-trifluorobutyl)butan-1-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4,4,4-Trifluorobutanal | HCID 2777083 | — |
| Product | 4,4,4-Trifluoro-N-(4,4,4-trifluorobutyl)butan-1-amine | HCID 187407 | — |
Reaction Steps
Following a procedure analogous to that for the synthesis of Example 106, 4,4,4-trifluorobutan-1-amine, HCl (598 mg, 4.00 mmol), Et3N (550 μL, 4.00 mmol) and 4,4,4-trifluorobutanal (504 mg, 4.00 mmol) provided a colorless oil which was used directly in the preparation of Example 129. MS(ESI+) m/z 192.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346795B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-5da0de8d1d4340aca2519c4beee7054b |
| Source note | uspto-grants-2016_05 |