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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 52916Generated: October 30, 2026

Ethyl 4-(1-hydroxyethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-5-carboxylate → HCID 178440096, compound

https://huagongshe.com/reaction/52916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-(1-hydroxyethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-5-carboxylateHCID 19036137—
SolventAcetic AcidHCID 176—
ProductHCID 178440096HCID 178440096101.7%

Reaction Steps

Following a procedure similar to that described in Example 35(c), 255 mg of ethyl 4-(1-hydroxyethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-5-carboxylate [prepared as described in step (a) above] was detritylated by treatment with 75% v/v aqueous acetic acid, to give 170 mg of the title compound as an amorphous solid. The Nuclear Magnetic Resonance Spectrum of this compound was identical with that of the compound obtained as described in Example 40(c).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616599
Source datasetuspto-grants-1997_04
ORD IDord-4ee8aec483be44eea978091c91b490f9
Source noteuspto-grants-1997_04