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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 529513Generated: October 29, 2026

1-(Bromomethyl)-3-chlorobenzene → (S)-3-Amino-1-(3-chlorobenzyl)azepan-2-one hydrochloride

https://huagongshe.com/reaction/529513

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-3-chlorobenzeneHCID 69838—
Reactant(S)-3-amino-1-benzylazepan-2-one hydrochlorideHCID 68292429—
Product(S)-3-Amino-1-(3-chlorobenzyl)azepan-2-one hydrochlorideHCID 68292318—

Reaction Steps

(S)-3-Amino-1-(3-chlorobenzyl)azepan-2-one hydrochloride (190 mg, 0.657 mmol) was synthesized as described for the preparation of Intermediate 42 using 1-(bromomethyl)-3-chlorobenzene in step A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09346852B2
Source datasetuspto-grants-2016_05
ORD IDord-64148bddf62445fcbcbeb076fdc5a417
Source noteuspto-grants-2016_05