HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorophenylboronic acid → (S)-3-Amino-1-(4-chlorophenyl)azepan-2-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Reactant | (S)-3-amino-1-(3-chlorophenyl)azepan-2-one hydrochloride | HCID 68291572 | — |
| Product | (S)-3-Amino-1-(4-chlorophenyl)azepan-2-one hydrochloride | HCID 68292068 | — |
Reaction Steps
(S)-3-Amino-1-(4-chlorophenyl)azepan-2-one hydrochloride (35 mg, 0.127 mmol) was synthesized as described for the preparation of Intermediate 49 using 4-chlorophenylboronic acid in step A. Anal. Calcd. for C12H15ClN2O m/z 238.8. found: 239.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346852B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-edfda83a2ccd40babafe5ca6596d97b0 |
| Source note | uspto-grants-2016_05 |