HuagongsheHuagongshe Chemistry Print Report · For research reference only
(7S,10aR)-7-aminooctahydropyrido[1,2-a]azepin-6(7H)-one hydrochloride → (7S,11aS)-7-Aminooctahydro-1H-pyrido[1,2-a]azocin-6(2H)-one hydrogen chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (7S,10aR)-7-aminooctahydropyrido[1,2-a]azepin-6(7H)-one hydrochloride | HCID 86706215 | — |
| Reactant | (7S,11aR,Z)-7-Amino-3,4,7,8,9,11a-hexahydro-1H-pyrido[1,2-a]azocin-6(2H)-one hydrochloride | HCID 86706217 | — |
| Product | (7S,11aS)-7-Aminooctahydro-1H-pyrido[1,2-a]azocin-6(2H)-one hydrogen chloride | HCID 86706219 | — |
Reaction Steps
(7S,11aS)-7-Aminooctahydro-1H-pyrido[1,2-a]azocin-6(2H)-one hydrogen chloride (273 mg, 1.17 mmol) was synthesized as described for the preparation of Intermediate 54 using (7S,11aR,Z)-7-amino-3,4,7,8,9,11a-hexahydro-1H-pyrido[1,2-a]azocin-6(2H)-one hydrochloride. Anal. Calcd. for C11H20N2O m/z 196.2. found: 197.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09346852B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8a23ae6ed71c4fb88dc91005ccc6f0d0 |
| Source note | uspto-grants-2016_05 |