反应详情

To a round bottom flask was added (S)-tert-butyl 1-(2-methoxyphenyl)-2-oxoazepan-3-ylcarbamate (27 mg, 0.081 mmol), DCM (1 mL) and TFA (1 mL). The reaction mixture was stirred at rt for 2 hr. The reaction mixture was concentrated under reduced pressure and then dried under high vacuum to give (S)-3-amino-1-(2-methoxyphenyl)azepan-2-one trifluoroacetate (28 mg, 0.080 mmol, 100% yield) as an oil.

1. concentrationThe reaction mixture was concentrated under reduced pressure
2. customdried under high vacuum