反应详情

To a stirred solution of (R)-tert-butyl 6-hydroxyhexan-2-ylcarbamate (0.530 g, 2.44 mmol) in DCM (1.5 mL) was added TFA (1.88 mL, 24.4 mmol). The resulting clear solution was stirred at rt for 1 hr. The reaction was concentrated. The obtained oily residue was dried under vacuum to give (R)-5-aminohexan-1-ol trifluoroacetate as a light brown oil.

1. concentrationThe reaction was concentrated
2. customThe obtained oily residue was dried under vacuum