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HRID52964

反应详情

EQUATION

反应方程式

HRID 52964 的结构方程式

REACTANTS

反应物

3
结构：N#Cc1ccccc1-c1ccc(CBr)cc1
HCID1501912

4'-Bromomethyl-2-cyanobiphenyl

C14H10BrN

结构：CC(C)(C)[O-].[K+]
HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

结构：CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1
HCID178440079

未命名化合物

PRODUCTS

生成物

1
结构：CCCc1nc(C(C)(C)O)c(C(=O)OCC)n1Cc1ccc(-c2ccccc2C#N)cc1
HCID15461993

Ethyl 1-[(2′-cyano[1,1′-biphenyl]-4-yl)methyl]-4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate

C26H29N3O3

收率 95.3%

PROCEDURE

实验过程

Following a procedure similar to that as described in Example 68(a), but using 4.01 g of ethyl 4-(1-hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylate (prepared as described in Preparation 9), 5.0 g of 4'-bromomethylbiphenyl-2-carbonitrile and 1.97 g of potassium t-butoxide, 6.86 g of the title compound were obtained as crystals, melting at 92°-93° C.