反应详情

A 1-L eggplant shaped flask was charged with 22.4 g of sodium 2,4,6-triisopropylbenzoate (prepared in Synthesis Example 1-2), 31.1 g of triphenylsulfonium methylsulfate, 90 g of methyl isopropyl ketone, 90 g of 1-pentanol, and 40 g of water, which were stirred at room temperature for 1 hour. The organic layer was separated from the reaction mixture and washed with water. After washing, the organic layer was concentrated by distilling off the solvent. The liquid concentrate was crystallized from 300 g of diisopropyl ether. The crystal precipitate was filtered and dried, obtaining the target compound, triphenylsulfonium 2,4,6-triisopropylbenzoate as white crystal. Amount 40.4 g, yield 80%.

1. customThe organic layer was separated from the reaction mixture
2. washwashed with water
3. washAfter washing
4. concentrationthe organic layer was concentrated
5. distillationby distilling off the solvent
6. concentrationThe liquid concentrate
7. customwas crystallized from 300 g of diisopropyl ether
8. filtrationThe crystal precipitate was filtered
9. customdried