Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 53006Generated: October 28, 2026

Hydrochloric Acid → Ethyl 1-[4-(2-carboxyphenyl)phenyl]methyl-2-ethoxymethyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate

https://huagongshe.com/reaction/53006

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl 1-{4-[2-(t-butoxycarbonyl)phenyl]phenyl}methyl-2-ethoxymethyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylateHCID 19036121—
ProductEthyl 1-[4-(2-carboxyphenyl)phenyl]methyl-2-ethoxymethyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylateHCID 19036064—

Reaction Steps

Following a procedure similar to that described in Example 96(b), but using 600 mg of ethyl 1-{4-[2-(t-butoxycarbonyl)phenyl]phenyl}methyl-2-ethoxymethyl-4-(1-hydroxy-1-methylethyl)imidazole-5-carboxylate [prepared as described in step (a) above], 585 mg of the hydrochloride of the title compound were obtained as a foam-like solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05616599
Source datasetuspto-grants-1997_04
ORD IDord-e1d478edef0642a6b30dfa34bc60d29d
Source noteuspto-grants-1997_04