HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → Diethyl 2-ethoxymethylimidazole-4,5-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 19036214 | HCID 19036214 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Diethyl 2-ethoxymethylimidazole-4,5-dicarboxylate | HCID 19036215 | — |
Reaction Steps
A solution of the diethyl 2-ethoxymethylimidazole-4,5-dicarboxylate hydrochloride thus obtained in ethyl acetate was neutralized by the addition of a saturated aqueous solution of sodium hydrocarbonate. The ethyl acetate layer was separated, dried over anhydrous magnesium sulfate and concentrated by evaporation under reduced pressure, to give the title compound as crystals, melting at 71°-74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05616599 |
| Source dataset | uspto-grants-1997_04 |
| ORD ID | ord-182e341af4d4487fa018e43965633b48 |
| Source note | uspto-grants-1997_04 |