Trifluoroacetic acid → HCID 118276734, compound

Participants

Reaction Steps

2-(2-Isopropylpyrimidin-4-yl)-morpholine-4-carboxylic acid tert-butyl ester (256 mg, 833 μmol) was dissolved in 5 mL of dichloromethane and TFA (2 mL) was added. The solution was stirred at room temperature for 2 h. The solvents were evaporated. The residue was extracted with dichloromethane and 1N NaOH solution. The organic layer was dried over Na2SO4 and concentrated. The residue was dried under vacuum to afford 2-(2-isopropylpyrimidin-4-yl)-morpholine (175 mg) as a colorless oil. (M+H)+=208 m/e.

Provenance & Evidence