HRID53079

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID887

Methanol

CH4O

HCID21954228

未命名化合物

$结构：C/C=C(\C)C(=O)N[C@@H](c1ccccc1)[C@@H](O)C(=O)O[C@H]1C[C@@]2(O)[C@@H](OC(=O)c3ccccc3)[C@@H]3[C@]4(OC(C)=O)CO[C@@H]4C[C@H](O)[C@@]3(C)C(=O)[C@H](OC(C)=O)C(=C1C)C2(C)C.CC(=O)O[C@H]1C(=O)[C@@]2(C)[C@H]([C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C1C3(C)C)[C@]1(OC(C)=O)CO[C@@H]1C[C@@H]2O$

HCID86586153

未命名化合物

PRODUCTS

生成物

结构：CC(=O)O[C@H]1C(=O)[C@@]2(C)[C@H]([C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C1C3(C)C)[C@]1(OC(C)=O)CO[C@@H]1C[C@@H]2O

HCID36314

Paclitaxel

C47H51NO14

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

In this fraction, 8 components were identified using 5% it methanol in chloroform as a developing system and p-anisaldehyde/sulfuric acid as a visualizing reagent. Taxol-cephalomannine mixture appeared as a bluish-gray spot, with a Rf value of 0.62.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-56026acbb36c44b7b79da23bda29c459
来源数据集: uspto-grants-1997_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05618538
来源说明: uspto-grants-1997_04

反应 SMILES

CO.C(=O)C1C=CC(OC)=CC=1.S(=O)(=O)(O)O.[CH3:18][C:19]1[C@@H:36]([O:37][C:38]([C@H:40]([OH:57])[C@@H:41]([NH:48][C:49]([C:51]2[CH:52]=[CH:53][CH:54]=[CH:55][CH:56]=2)=[O:50])[C:42]2[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=2)=[O:39])[CH2:35][C@:31]2([OH:58])[C:32]([CH3:34])([CH3:33])[C:20]=1[C@@H:21]([O:76][C:77]([CH3:79])=[O:78])[C:22]([C@@:24]1([CH3:75])[C@H:29]([C@@H:30]2[O:59][C:60]([C:62]2[CH:63]=[CH:64][CH:65]=[CH:66][CH:67]=2)=[O:61])[C@:28]2([O:70][C:71]([CH3:73])=[O:72])[CH2:68][O:69][C@@H:27]2[CH2:26][C@@H:25]1[OH:74])=[O:23].C/C=C(/C(N[C@H]([C@@H](O)C(O[C@@H]1C(C)=C2C(C)(C)[C@](O)([C@@H](OC(C3C=CC=CC=3)=O)[C@@H]3[C@]4(OC(C)=O)CO[C@@H]4C[C@H](O)[C@@]3(C)C([C@@H]2OC(C)=O)=O)C1)=O)C1C=CC=CC=1)=O)\C>C(Cl)(Cl)Cl>[CH3:18][C:19]1[C@@H:36]([O:37][C:38]([C@H:40]([OH:57])[C@@H:41]([NH:48][C:49]([C:51]2[CH:56]=[CH:55][CH:54]=[CH:53][CH:52]=2)=[O:50])[C:42]2[CH:43]=[CH:44][CH:45]=[CH:46][CH:47]=2)=[O:39])[CH2:35][C@:31]2([OH:58])[C:32]([CH3:33])([CH3:34])[C:20]=1[C@@H:21]([O:76][C:77]([CH3:79])=[O:78])[C:22]([C@@:24]1([CH3:75])[C@H:29]([C@@H:30]2[O:59][C:60]([C:62]2[CH:67]=[CH:66][CH:65]=[CH:64][CH:63]=2)=[O:61])[C@:28]2([O:70][C:71]([CH3:73])=[O:72])[CH2:68][O:69][C@@H:27]2[CH2:26][C@@H:25]1[OH:74])=[O:23]