HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → (2,6-Dimethylpyridin-3-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-(Chloromethyl)-2,6-dimethylpyridine | HCID 62830608 | — |
| Product | (2,6-Dimethylpyridin-3-yl)methanamine | HCID 21065647 | — |
Reaction Steps
The solution of 3-(chloromethyl)-2,6-dimethylpyridine (850 mg, 5.5 mmol) in ammonia solution (10 mL) was stirred at 90° C. for 2 hours and then concentrated to give the crude product which was used for next step directly without further purification. LCMS (ESI) m/z=137.1 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353104B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-7da4fda518304ba69f8a1c03d4ea69fe |
| Source note | uspto-grants-2016_05 |