Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (6-Methylpyridazin-3-yl)methanamine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 6-Methylpyridazine-3-carbonitrile | HCID 13642941 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (6-Methylpyridazin-3-yl)methanamine hydrochloride | HCID 90419251 | — |
반응 단계
To a solution of compound 2 (250 mg, 2.38 mmol) in MeOH (20 mL) was added 6N HCl (5 mL) followed by Pd/C (100 mg). The reaction mixture was kept on Parr shaker for 2 h at 40 psi. The reaction mixture was filtered through celite and washed with 5 mL of MeOH and the filtrate was concentrated to give compound 3 as a dark brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09353104B2 |
| 출처 데이터셋 | uspto-grants-2016_05 |
| ORD ID | ord-cf8b83c62f094e8cb8d32193204aa5e5 |
| 출처 메모 | uspto-grants-2016_05 |