HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → 3-(Bromomethyl)pyrazolo[1,5-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | Pyrazolo[1,5-a]pyridin-3-ylmethanol | HCID 14134319 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-(Bromomethyl)pyrazolo[1,5-a]pyridine | HCID 76852202 | — |
Reaction Steps
To the solution of pyrazolo[1,5-a]pyridin-3-ylmethanol (2) (50 mg, 0.338 mmol) in DCM (2 mL) was added PBr3 (36.58 mg, 0.135 mmol) at room temperature for 30 min. The reaction solution was used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353104B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-11575ae34fdd45909ee7e4de3a874ed3 |
| Source note | uspto-grants-2016_05 |