HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxamide → N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1H-indazole-5-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxamide | HCID 67985165 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Solvent | Thioanisole | HCID 7520 | — |
| Product | N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1H-indazole-5-carboxamide | HCID 57410536 | — |
Reaction Steps
A solution of N-(3-benzoyl-3-hydroxycyclohexyl)-3-(2-methylpyridin-4-yl)-1-trityl-1H-indazole-5-carboxamide in a mixture of TFA (1 mL) and thioanisole (0.5 mL) was stirred at room temperature for 20 minutes, and then concentrated. The product was obtained after purification by reverse phase HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09351965B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-0a537cd7394e4591a5c13a0706efb9dc |
| Source note | uspto-grants-2016_05 |