Hydrochloric Acid → HCID 68074354, compound

HRID 530864Notes

Reaction equation

HRID 530864 reaction equation
Cl.C(OC(=O)[NH:8][CH:9]1[CH2:14][CH2:13][CH2:12][C:11]([CH2:16][N:17]2[C:25]3[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=3)[CH:19]=[N:18]2)([OH:15])[CH2:10]1)(C)(C)C>O1CCOCC1>[N:17]1([CH2:16][C:11]2([OH:15])[CH2:12][CH2:13][CH2:14][C@@H:9]([NH2:8])[CH2:10]2)[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[N:18]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 77454469HCID 77454469, compound

Product 1

HCID 68074354HCID 68074354, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

In a flask, hydrochloric acid in dioxane (4M, 2 mL) was added to tert-butyl-3-((1H-indazol-1-yl)methyl)-3-hydroxycyclohexylcarbamate (50 mg), and the reaction was stirred for 30 minutes. The resulting solution was concentrated in vacuo. The crude product was progressed to the next step without further purification.

Workup

  1. concentrationThe resulting solution was concentrated in vacuo
  2. customThe crude product was progressed to the next step without further purification

Sources & evidence

ORD record
ord-88914f2a1fdd480388807d26081f5500
Source dataset
uspto-grants-2016_05
Patent number
US09351965B2

Reaction notes

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