HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tert-butyl 3-(benzylamino)-3-(2-fluorobenzyl)cyclohexylcarbamate | HCID 67983661 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | N1-benzyl-1-(2-fluorobenzyl)cyclohexane-1,3-diamine | HCID 77454515 | — |
Reaction Steps
tert-butyl 3-(benzylamino)-3-(2-fluorobenzyl)cyclohexylcarbamate was stirred in a solution of HCl in dioxane (4 M) at room temperature for 5 hours. The product, HCl salt of N1-benzyl-1-(2-fluorobenzyl)cyclohexane-1,3-diamine, was obtained after evaporation of solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09351965B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-8097c30470ab4d3f9414952fc6b4833d |
| Source note | uspto-grants-2016_05 |