Sucrose → Sucrosofate

HRID 53104Notes

Reaction equation

HRID 53104 reaction equation
N1C=CC=CC=1.[S:7](=[O:10])(=[O:9])=[O:8].[CH2:11]([OH:33])[C@H:12]1[O:17][C@H:16]([O:18][C@:19]2([CH2:28][OH:29])[O:23][C@H:22]([CH2:24][OH:25])[C@@H:21]([OH:26])[C@@H:20]2[OH:27])[C@H:15]([OH:30])[C@@H:14]([OH:31])[C@@H:13]1[OH:32]>O>[CH2:11]([O:33][S:7]([OH:10])(=[O:9])=[O:8])[C@H:12]1[O:17][C@H:16]([O:18][C@:19]2([CH2:28][O:29][S:7]([OH:10])(=[O:9])=[O:8])[O:23][C@H:22]([CH2:24][O:25][S:7]([OH:10])(=[O:9])=[O:8])[C@@H:21]([O:26][S:7]([OH:10])(=[O:9])=[O:8])[C@@H:20]2[O:27][S:7]([OH:10])(=[O:9])=[O:8])[C@H:15]([O:30][S:7]([OH:10])(=[O:9])=[O:8])[C@@H:14]([O:31][S:7]([OH:10])(=[O:9])=[O:8])[C@@H:13]1[O:32][S:7]([OH:10])(=[O:9])=[O:8]

Participants

4

Reactant 2

HCID 5988SucroseHCID 168533Sulfur trioxide-pyridine

Product 1

HCID 444237Sucrosofate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
65 °C

Procedure

254.7 g (1.6 mol) of sulfur trioxide pyridine were slurried in 1300 ml of water-free pyridine. With stirring, 68.5 g (0.2 mol) of sucrose were added. The reaction mixture was heated to 65° C. and kept at this temperature for 240 minutes. As the reaction proceeded, the substance was separated as a thick flowing oil. When the reaction was terminated, the agitator was stopped, the pyridine phase was decanted, and the oily phase was dissolved in 600 ml of ion-exchanged water.

Workup

  1. customthe substance was separated as a thick
  2. customWhen the reaction was terminated
  3. customthe pyridine phase was decanted
  4. dissolutionthe oily phase was dissolved in 600 ml of ion-exchanged water

Sources & evidence

ORD record
ord-36461e8532db42809efa1d16c749e9dc
Source dataset
uspto-grants-1997_04
Patent number
US05618798

Reaction notes

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