反应详情

In a 250 mL single-neck round-bottom flask equipped with reflux condenser, 3,4-thiophenedicarboxylic acid (Frontier Scientific, 4.000 g, 0.02325 mol) was heated to 120° C. with acetic anhydride for 6 hours. The reaction was then cooled to room temperature and the solvent was removed under reduced pressure to yield a dark brown solid. The crude product was recrystallized from toluene to yield pale yellow needles in quantitative yield.

1. customIn a 250 mL single-neck round-bottom flask equipped
2. temperaturewith reflux condenser
3. customthe solvent was removed under reduced pressure
4. customto yield a dark brown solid
5. customThe crude product was recrystallized from toluene
6. customto yield pale yellow needles in quantitative yield