HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118523895, compound → HCID 118523928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118523895 | HCID 118523895 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 118523928 | HCID 118523928 | 205% |
Reaction Steps
Using similar reaction conditions as described in step-ii of example-7, tert-butyl 4-(4-(3-(1-phenethyl-1H-pyrazol-4-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)piperazine-1-carboxylate (200 mg, 0.290 mmol) was deprotected in TFA/DCM (2/5 ml) to afford 175 mg (85.7% yield) of the titled compound. MS: m/z=589.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09353107B2 |
| Source dataset | uspto-grants-2016_05 |
| ORD ID | ord-2ecf7bb3071c41049f649e5af5fb85d6 |
| Source note | uspto-grants-2016_05 |