HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Bromo-3-methylphenyl)methanol → 4-Bromo-3-methylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Bromo-3-methylphenyl)methanol | HCID 10987288 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Bromo-3-methylbenzaldehyde | HCID 10921521 | 89.4% |
Reaction Steps
To a solution of (4-bromo-3-methylphenyl)methanol (420 mg, 2.09 mmol) in DCM (6 mL) at rt was added MnO2 (1.82 g, 20.9 mmol). The reaction mixture was stirred for 12 h, filtered and concentrated under reduced pressure to give 4-bromo-3-methyl-benzaldehyde (372 mg; yield 89%) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08853186B2 |
| Source dataset | uspto-grants-2014_10 |
| ORD ID | ord-5ba3fd3e45074ef5a6c2f11c600759b0 |
| Source note | uspto-grants-2014_10 |