tert-Butyl 2-(5-fluoro-2-nitrophenoxy)propylcarbamate → tert-Butyl 2-(2-amino-5-fluorophenoxy)propylcarbamate

関与物質

反応手順

To a solution of tert-butyl 2-(5-fluoro-2-nitrophenoxy)propylcarbamate (3.1 g) in MeOH (5 ml) was added 10% palladium on carbon (300 mg) and the reaction mixture was hydrogenated at room temperature at 50 psi. The catalyst was filtered off and the filtrate was concentrated in vacuo.

情報源と証拠