Iodoethane → 2-Amino-1-ethylpyridinium iodide

In a 1 L three-necked flask fitted with a reflux condenser were placed 28.2 g of 2-aminopyridine and 60.8 g of iodoethane, and the mixture was stirred under reflux for 2 hours. The reaction mixture was stirred at room temperature for another hour, and the resulting precipitate was filtered under reduced pressure and washed with ethyl acetate (50 ml×2). The residue was dried at room temperature for 3 hours.

1. customIn a 1 L three-necked flask fitted with a reflux condenser
2. temperatureunder reflux for 2 hours
3. stirringThe reaction mixture was stirred at room temperature for another hour
4. filtrationthe resulting precipitate was filtered under reduced pressure
5. washwashed with ethyl acetate (50 ml×2)
6. customThe residue was dried at room temperature for 3 hours

ORD record

ord-0685590cd6a64f099699b54fca00ae51

Source dataset

uspto-grants-1997_04

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05618831