反应详情

温度

60 °C

In a 200 ml three-necked flask were placed 1.8 g of 2-aminopyrimidine and 5.6 g of methyl p-toluenesulfonate, and the mixture was stirred at 120° C. for 3 hours. After the resulting mixture was cooled to 60° C., 100 ml of acetone was added and the mixture was stirred at room temperature for 1 hour. The crystals were filtered under reduced pressure, washed with acetone, and dried at room temperature under reduced pressure.

1. customIn a 200 ml three-necked flask were placed
2. filtrationThe crystals were filtered under reduced pressure
3. washwashed with acetone
4. customdried at room temperature under reduced pressure