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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 532436Generated: October 30, 2026

p-Fluoronitrobenzene → 8-(3-Fluoropropyl)-3-(4-nitrophenoxy)-8-azabicyclo[3.2.1]octane

https://huagongshe.com/reaction/532436

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluoronitrobenzeneHCID 9590—
Reactant8-(3-Fluoropropyl)-8-azabicyclo[3.2.1]octan-3-olHCID 68941407—
Product8-(3-Fluoropropyl)-3-(4-nitrophenoxy)-8-azabicyclo[3.2.1]octaneHCID 68943225—

Reaction Steps

8-(3-Fluoropropyl)-8-azabicyclo[3.2.1]octan-3-ol was reacted with 1-fluoro-4-nitrobenzene by method D. The product with the molecular weight of 308.35 (C16H21FN2O3) was obtained in this way; MS (ESI): 308 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853208B2
Source datasetuspto-grants-2014_10
ORD IDord-c23de2dd4a2a4ffe8816665fccaa5477
Source noteuspto-grants-2014_10