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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 532442Generated: November 1, 2026

1-Pyrrolidineethanol → 1-[2-(2-Fluoro-4-nitrophenoxy)ethyl]pyrrolidine

https://huagongshe.com/reaction/532442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-PyrrolidineethanolHCID 76288—
Reactant1,2-Difluoro-4-nitrobenzeneHCID 123053—
Product1-[2-(2-Fluoro-4-nitrophenoxy)ethyl]pyrrolidineHCID 25248766—

Reaction Steps

3,4-Difluoronitrobenzene was reacted with 1-(2-hydroxyethyl)pyrrolidine by method D1. The product with the molecular weight of 254.26 (C12H15FN2O3) was obtained in this way; MS (ESI): 255 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08853208B2
Source datasetuspto-grants-2014_10
ORD IDord-d435328e97c14320be2455ff80b7337d
Source noteuspto-grants-2014_10