Bromomethylcyclopropane → HCID 57618792, compound

HRID 532449Notes

Reaction equation

HRID 532449 reaction equation
[CH3:1][N:2]([CH3:24])[CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N:12]2[C:17](=[O:18])[C:16]3[S:19][C:20]([CH2:22][OH:23])=[CH:21][C:15]=3[N:14]=[CH:13]2)=[CH:8][CH:7]=1.[CH:25]1([CH2:28]Br)[CH2:27][CH2:26]1>>[CH:25]1([CH2:28][O:23][CH2:22][C:20]2[S:19][C:16]3[C:17](=[O:18])[N:12]([C:9]4[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH2:3][N:2]([CH3:24])[CH3:1])=[CH:7][CH:8]=4)[CH:13]=[N:14][C:15]=3[CH:21]=2)[CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 81503BromomethylcyclopropaneHCID 68941363HCID 68941363, compound

Product 1

HCID 57618792HCID 57618792, compound

Procedure

3-[4-(2-Dimethylaminoethoxy)phenyl]-6-hydroxymethyl-3H-thieno[3,2-d]pyrimidin-4-one was reacted with cyclopropylmethyl bromide by method V. The product with the molecular weight of 399.52 (C21H25N3O3S) was obtained in this way; MS (ESI): 400 (M+H+).

Workup

  1. customThe product with the molecular weight of 399.52 (C21H25N3O3S) was obtained in this way

Sources & evidence

ORD record
ord-30e5c76a449f4818be088d746230d7e6
Source dataset
uspto-grants-2014_10
Patent number
US08853208B2

Reaction notes

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