HCID 57618669, compound → HCID 57618714, compound

Participants

Reaction Steps

Palladium on carbon (40 mg) was added to a solution of 6-((Z)-2-ethoxyvinyl)-3-[3-fluoro-4-(2-pyrrolidin-1-ylethoxy)phenyl]-3H-thieno[3,2-d]pyrimidin-4-one (73 mg) in methanol (4 mL), and the mixture was hydrogenated until starting material was no longer present. The mixture was filtered and the filtrate was concentrated. The product with the molecular weight of 431.53 (C22H26FN3O3S) was obtained in this way; MS (ESI): 432 (M+H+).

Provenance & Evidence