反应详情

To a warm solution of [1-(1-methylethyl)-4-piperidinyl]methyl[2-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl]carbamate (120 mg) in the minimum amount of ethyl acetate was added a solution of maleic acid (36.9 mg) in the minimum amount of warm methanol (2 ml). Concentration in vacuo left a white oily residue which was triturated twice in ether (10 ml). The resulting white powder was filtered and dried in vacuo to yield the title compound as a light brown solid (107 mg), m.p. 89°-93°.

1. concentrationConcentration in vacuo
2. waitleft a white oily residue which
3. customwas triturated twice in ether (10 ml)
4. filtrationThe resulting white powder was filtered
5. customdried in vacuo