反应详情

温度

25 °C

5-(2,4-Dimethoxy-benzoyl)-5,6-dihydro-cyclopenta[b]thiophen-4-one (1.12 g, 3.69 mmol), hydrazine monohydrate (0.7 mL, 22 mmol), glacial acetic acid (0.6 mL) and ethanol (10 mL) was heated at 100° C. under nitrogen for 4 hr. The mixture was cooled to 25° C. and concentrated under reduced pressure to give a solid which was recrystallized from ethanol to provide the corresponding 6-(2,4-Dimethoxy-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (2.5 g, 3.1 mmol) as yellow solid in 85% yield.

1. concentrationconcentrated under reduced pressure
2. customto give a solid which
3. customwas recrystallized from ethanol