反应详情

温度

100 °C

2-Bromo-6-(4-methoxy-phenyl)-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.12 g, 0.25 mmol) was dissolved in MeOH and treated with concentrated HCl (0.08 mL, 2.5 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 6-(4-Methoxy-phenyl)-2-phenyl-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalene (0.04 g, 0.11 mmol) as white solid in 46% yield.

1. temperatureThe solution was cooled to room temperature
2. filtrationthe resultant precipitate was filtered
3. washwashed with MeOH
4. concentrationconcentrated under reduced pressure