反应详情

温度

100 °C

3-[6-(4-Methoxy-phenyl)-4-(2-trimethylsilanyl-ethoxymethyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalen-2-yl]-phenylamine (0.36 g, 0.7 mmol) was dissolved in MeOH and treated with concentrated HCl (0.26 mL, 7.0 mmol). The reaction mixture was heated at 100° C. for 4 hr. The solution was cooled to room temperature and the resultant precipitate was filtered, washed with MeOH and concentrated under reduced pressure to provide the corresponding 3-[6-(4-Methoxy-phenyl)-4,7-dihydro-1-thia-4,5-diaza-cyclopenta[a]pentalen-2-yl]-phenylamine (0.26 g, 0.67 mmol) as yellow solid in 96% yield.

1. temperatureThe solution was cooled to room temperature
2. filtrationthe resultant precipitate was filtered
3. washwashed with MeOH
4. concentrationconcentrated under reduced pressure